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Contraindications and Precautions Consider avoiding BPC-157 if you have: History of cancer or active malignancy Pregnancy or breastfeeding (no safety data) Competitive athletic status (WADA prohibits peptides) Known sensitivity to peptide products Severe cardiovascular disease (limited data) Blood pressure monitoring may be prudent given the nitric oxide modulation effects

This dual mechanism may enhance outcomes for GERD specifically compared to purely systemic delivery

GI endocannabinoids system The central and peripheral endogenous cannabinoid system appears to play a role in feeding regulation