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As early diagnosis and treatment prevent development of metabolic crisis and cardiomyopathy, most NBS-diagnosed patients are expected to live a normal life span free of symptoms

Phase 2 trial of bortezomib in combination with rituximab plus hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternating with bortezomib, rituximab, methotrexate, and cytarabine for untreated mantle cell lymphoma
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(PubMed) Diez-Ricote L, San-Cristobal R, Concejo MJ, et al