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Endocrinology 153 , 37353746 (2012)

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17 Normal physiology of aminotransferases ALT and AST catalyze the reversible transfer of amino groups from L-alanine and L-aspartate to L-glutamate, and produce pyruvate and oxaloacetate (Fig

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MannKinds inhaled insulin programme, which progressed successfully through phase III clinical testing and gained FDA approval as Afrezza, represents another example of advanced control of particle size, density and dispersibility to enable reliable pulmonary delivery of therapeutics

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