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For an example, the mutation of M351 causes the weak resistance to imatinib
10.1016/j.freeradbiomed.2006.05.019 14 BuetlerT
It tends to accumulate over time as multiple stressors pile up faster than the body can recover from them
Mouse models of cystathionine beta-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia
