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Epigenetic diet: impact on the epigenome and cancer
By combining GLS1 inhibition (e.g., CB-839) and NQO1 -bioactivatable drugs (e.g., -lap, ARQ761), we exploit the reliance of PDA on glutamine for redox balance, as well as the tumor-selective overexpression of NQO1 through the use of a unique agent that is bioactivated to induce cell death
Aschner, M., Eberle, N
polyphenol-based treatments, including GA and curcumin consistently demonstrated their ability to modulate gut microbiota composition across various studies
