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Description
This preparatory step may involve the temporary protection of the quaternary ammonium group or selective activation using coupling reagents under controlled pH and temperature conditions to prevent racemization or degradation of the stereogenic centre
Simultaneously, the hydride ion is transferred from C-1 of glucose 6-phosphate to the C-4 position of the nicotinamide ring of NADP + to form NADPH

2019;575(7784):693-698.[DOI] 80

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