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Description
Loss-of-function missense mutations as well as single nucleotide polymorphisms in the genes encoding K ir 4.1 and AQP4 (which is selectively astroglial and operates in concert with K ir 4.1) are linked to epilepsy in humans
An extended insertion known as the receptor-binding motif (RBM) from the core contains two short strands, two helices, and loops
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