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453 UC patients who take budesonide twice daily show obvious improvements in clinical symptoms, a reduction in rectal bleeding, and an increase in the endoscopic remission rate

Science ((1979)) 363:11501151 Hammond DE, Mageean CJ, Rusilowicz EV, Wickenden JA, Clague MJ, Prior IA (2015a) Differential reprogramming of isogenic colorectal cancer cells by distinct activating KRAS mutations
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Even if you suspect the medication lost some potency, taking more than prescribed carries its own risks, particularly gastrointestinal side effects like constipation or increased burping
