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Chronotherapy has been clinically implemented in various disease areas, including hypertension, high cholesterol, bronchial asthma, and certain types of cancer (Man et al., 2021)

The data that support the findings of the present study are available within the article and its Supplementary Information
Even though oral treatments of the methyl donor SAM ameliorated ASD-associated deficits in valproic acid (VPA)-exposed mice by reversing epigenetic changes, there has been limited success thus far in the development of preventative agents similar to SAM for the clinical management of ASD in humans

Abbreviations References 1 AkbarianS.HuntsmanM
