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1 A possible association between hookworm or whipworm infection and liver cancer has been reported, and cats with chronic cholangitis may have an increased predisposition to biliary carcinoma.7, 13 Several liver mitogens and tumor suppressor genes such as epidermal growth factor, TGF-, vascular endothelial growth factor (VEGF), p53, and TGF- and its receptors (TGF--r) have been associated with liver cancers in humans and these may play a similar role in the dog.14, 15, 16, 17 In human medicine a small percentage of HCCs or cholangiocarcinomas originate from hepatic progenitor stem cells

Front Psychiatry 10:443755 Sarris J (2019) Nutritional psychiatry: from concept to the clinic

2 This classification defines the tumor histological type according to the predominant cytological type

However, for low-internalizing agonists, such as ARM390 and JNJ20788560, arrestin 3 facilitates the rate of receptor resensitization