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5) via its activity on histone deacetylases and is capable of influencing genomic administration

Dietary green tea extract lowers plasma and hepatic triglycerides and decreases the expression of sterol regulatory element-binding protein-1c mRNA and its responsive genes in fructose-fed, ovariectomized rats

Because malonyl-coenzyme A serves as a critical substrate for fatty acid synthesis and simultaneously acts as an endogenous inhibitor of carnitine palmitoyltransferase 1 (CPT1), suppression of ACC activity induces metabolic remodeling at both the synthetic and oxidative ends of lipid metabolism (41, 42)