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Clinical and preclinical investigations have shown that inhaled nanoparticlebased therapeutics can achieve effective treatment outcomes with reduced drug doses or dosing frequency, and through combination strategies that codeliver multiple therapeutic agents with different targets

doi: 10.1038/s41586-021-03892-7

NMN supplementation in mice also improved mitochondrial morphology through DRP1, and reduced ROS through antioxidant response expression 113

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