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Large amounts of IL-6 are produced by macrophages and endothelial cells, activating T cells and other immune cells and thereby creating a positive feedback-loop that results in a cytokine storm, inducing the release of many more cytokines and chemokines but also upregulating acute phase proteins
Supplementary material The Supplementary Material for this article can be found online at: References Chen J., Wang M., Joyce A., DeFranco D., Kavosi M., Xu X., et al
Hoge did not mention another part of the study that cast a less-positive light on the updated shot
Gao L, Zhou W, Symmes B, Freed CR
