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Content of toxic components of cigarette, cigarette smoke vs cigarette butts: A comprehensive systematic review, Science of the Total Environment (2022) Free radicals, antioxidants in disease and health, International Journal of BioMedical Science (2008) Smoking status in relation to serum folate and dietary vitamin intake, Tobacco Induced Diseases (2008) Cigarette smoking-nutritional implications, Progress in Food and Nutrition Sciences (1991) Vitamin C enhances antiviral functions of lung epithelial cells, Biomolecules (2021) Unhealthy smokers: scopes for prophylactic intervention and clinical treatment, BMC Neuroscience (2017) Vitamin C, National Library of Medicine Vitamin C prevents cigarette smokeinduced pulmonary emphysema in mice and provides pulmonary restoration, American Journal of Respiratory Cell and Molecular Biology (2013) Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation, Free Radical Biology and Medicine (2006) Vitamin D deficiency, smoking, and lung function in the normative aging study, American Journal of Respiratory and Critical Care Medicine (2012) Effect of cigarette smoking on serum homocysteine and vitamin B12 level in male population of Udaipur, Biochemistry and Analytical Biochemistry (2016) The role of zinc in the pathogenesis of lung disease, Nutrients (2022) Cigarette smoking, cadmium exposure, and zinc intake on obstructive lung disorder, Respiratory Research (2010) -Carotene supplementation and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: The role of tar and nicotine, Nicotine & Tobacco Research (2018) Beta carotene, Mayo Clinic Unhealthy smokers: scopes for prophylactic intervention and clinical treatment, BMC Neuroscience (2017) Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice

Supported by: US Department of the Army grant DAMD17-98-1-8621 and the Office of Research and Development, Medical Research Service, Department of Veterans Affairs (GWR), Hawaii Community Foundation Grant 20071373 (FPB), NIH RO1 NS40302 (MJB), NIH R24 DA027318 (MJB/FPB), NIH U01 AG019349 (LRW), and NIH G12 RR003061 which supports the JABSOM histology/imaging core facility

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