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Description
In celiac disease, the human leukocyte antigens HLA DQ2 and HLA DQ8 bind with gluten peptides and induce an immune reaction that leads to disease development

Numerous studies have demonstrated its cardioprotective effects in various pathological conditions, including ischemia-reperfusion injury, diabetic cardiomyopathy, and drug-induced myocardial injury, primarily through its ability to mitigate apoptosis and oxidative stress

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Thus, stimulated inflammatory cells present in the inflamed mucosa are capable of producing superoxide anion and hydrogen peroxide (Harris et al, 1992
