dihexa deamidation - an overview Schematic representation of deamidation pathways.
Description
Cagrilintide as a standalone monotherapy is being evaluated in the RENEW Phase 3 program
For instance, in a murine model, Hofmann et al

It targets adipose tissue directly, including stubborn abdominal fat, and because it does not trigger catabolic pathways, lean muscle stays intact
All measurements were conducted in triplicate, and mean values were reported
