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[PMC free article] [PubMed] [Google Scholar] 2.Skin hyperpigmentation as the presenting symptom of subacute combined degeneration of the spinal cord

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Iron chelation - Apart from regular blood transfusions, iron chelation therapy in the form of deferoxamine (desferal) subcutaneous infusion (with a pump), oral tablets like deferiprone (kelfer), deferasirox (few common brands are asunra, desirox, defrijet or oleptiss) is required as the excess iron from blood transfusions accumulate in the vital organs causing severe damage and even death due to cardiac and liver failure

Muscle cramps and spasms can be incredibly frustrating and disrupt your daily life