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& Dyess, G

CERTIFICATE OF ANALYSIS Product name 5-amino-1-methylquin olin-1-iumiodide CAS NO 42464-96-0 Molecular formula C10H11IN2 Molecular weight 286.11 Quantity Test based on enterprise standard Test Item Specification Result Appearance Reddish brown solid powder Conforms PurityHNMR 98.0% Conforms Purity(HPLC) 98.0% 99.4% 400MHz 1H Consistent Consistent MS 159.21.0 158.2 Storage In an air tight container,protected from light at temperature 2-8

Semaglutide enables the body to use glucose more efficiently

Reactions were performed with 0.5 M catechol substrate COMT-S01, 1 M radiolabelled S-adenosyl-L-[methyl- 3 H] methionine (SAM) co-substrate, and recombinant human COMT enzyme