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Side Effects: What You Need to Know Hydroquinone Side Effects Hydroquinone misuse or prolonged use can lead to: Chronic irritation Uneven whitening or patchiness Thinning of the skin Rebound darkness after stopping Exogenous ochronosis (rare but serious bluish-black discoloration) These risks increase when hydroquinone is: Used without medical supervision Applied longer than recommended Combined with sun exposure Mixed with steroid creams Alpha Arbutin Side Effects Alpha arbutin is considered one of the safest brightening agents available

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Shape topical (cream, serum containing Glutathione) The skin care products contain Glutathione is also a popular choice for those who want to improve skin pigmentation in a gentle way, however, due to Glutathione hard osmosis through the skin, the efficiency of the method is not typically taken orally or by injection