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As with any metabolic intervention, finding the right approach requires patience and professional guidance

Antibiotics such as Azithromycin, Amoxicillin, Clindamycin, Vancomycin, Cephalexin, and Ciprofloxacin are commonly used to treat bacterial infections but also affect the beneficial bacteria and disrupt gut homeostasis by reducing diverse beneficial bacterial strains such as Bifidobacterium and Lactobacillus (Duan et al

Biochemical analysis Hepatic glycogen content, hepatic non-esterified fatty acid (NEFA) content, activities of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum, and glucose content in serum were detected using reagent kits from Nanjing Jiancheng Bioengineering Institute (Cat# A043-1-1, Cat# A042-2-1, Cat#C009-2-1, Cat# C010-2-1, Cat# F006-1-1

LDLR Polymorphisms in the LDLR gene are associated with familial hypercholesterolemia, atherosclerosis, and obesity.111,112 However, in the context of HCV infection, LDLR recognizes the E2 viral protein and allows the HCV entry to the cell.33 Two SNPs in the LDLR gene rs1433099A/G and rs2569540G/C are associated with lower viral load and lower levels of LDL and cholesterol in patients genotype 1 and 4.113 It has been reported an interaction between IL28B and LDLR.114 Since IFN induces expression of LDLR gene that could be a reason why IFN treated patients have reduced serum cholesterol levels.115 Furthermore, intracellular levels of HCV-RNA in primary hepatocytes correlate with LDLR mRNA expression, and the uptake of LDL particles.33 Since IFN can stimulate soluble form of LDLR in cell culture and that soluble LDLR can inhibit HCV infectivity, LDLR can exert an antiviral effect against HCV infection.116 Impact of Dietary Components On HCV Replication The effect of dietary components on the HCV life cycle is mostly unknown