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After CBS deletion, resulting in decreased expression of antioxidant enzymes such as NRF2, MnSOD, and GPX4, and increased expression of GR and Catalase
Across both readouts, S10A closely phenocopied WT, whereas S10D displayed a selective flux defect consistent with a constitutive phospho-mimetic state

Recent Patents on Anti-Cancer Drug Discovery , 11 ( 2 ), 184196
