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Interleukin-6 The major source of interleukin-6 (IL-6) seen in IBD has been shown to be intestinal epithelial cells and lamina propria mononuclear cells.48 Recent studies indicate the involvement of IL-6 in intestinal TJ regulation.49 IL-6 increases paracellular permeability selectively to cations, but not to macromolecules, with an increase in pore-forming claudin-2 in intestinal epithelial cells, which requires the mitogen-activated protein kinase (MEK)/extracellular signal-regulated kinase (ERK) and PI3K/Akt signaling activations

Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults

Appreciation is extended to Supaphich Suksa, PharmD, for critical review of the manuscript, and to the Guest Editor(s) for the invitation to contribute to the special collection Women in Translational Neuroscience 2025

Evolutionary mismatch and chronic psychological stress