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For topical applications, skin barrier penetration and long-term local tolerance are primary concerns
Katiyar SK, Gaur SN, Solanki RN, Sarangdhar N, Suri JC, Kumar R, et al
10.1111/j.1476-5381.1988.tb11621.x Br
10.1073/pnas.0504423102 170 WangJ
