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Research Grade The Science Behind 5-Amino-1MQ Mechanism of Action 5-Amino-1MQ selectively inhibits NNMT (IC ~1.2 M), the enzyme that diverts nicotinamide away from the NAD+ salvage pathway
Future studies should take these considerations into account to advance understanding in this field

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On one hand, the pro-inflammatory potential of M2 phenotype macrophages are dramatically descended, due to weakened tumor antigen presenting ability [37] and the secretions of suppressor factors such as IL-12 [38]