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Although the exact mechanism is unknown, this rise in melanocyte activity has been shown to be stimulated by prostanoids, cytokines, chemokines, and other inflammatory mediators as well as reactive oxygen species that are released during the inflammatory process
Mol Gen Genet 172:1724 Mahon G, Green M, Middleton B et al (1989) Analysis of data from microbial colony assays
When stored properly at 2C to 8C, a solution reconstituted with BAC water will remain potent for several weeks
Most protocols last 46 weeks, but chronic issues may require cycling every few months
