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Car-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances

Although these concentrations are lower than GSH levels, they suggest that NAC possesses some degree of direct antioxidant activity ( 2.3 Disulfide bond reducing agent NAC participates in a conventional sulfhydryldisulfide exchange reaction, serving as an effective reducing agent for protein disulfide bonds

Glutathione is often called the bodys master antioxidant because it sits at the center of detoxification, immune defense, and cellular repair

Mitochondria isolated from livers of GPx1 deficient mice, however, were found to have an increased release of hydrogen peroxide, with a decreased respiratory control ratio [174]