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Doxycycline hydrochloride induces apoptosis , inhibits autophagy and EMT , downregulates stem cell markers, and activates the PI3K-AKT pathway, thereby effectively inhibiting the viability and proliferation of cancer cells such as breast cancer cells

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This problem of local mCRP formation has been explored in various studies, but the contribution of local conversions to the total mCRP in tissues and bloodstream is unknown because, up to now, most research refers to CRP and does not distinguish between the various isoforms (not only mCRP or pCRP, but also monomers and polymers) in other ways in CRP degradation