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Nonetheless, considering the clinical relevance of GLP-1 therapies and their potential impact on energy balance beyond food intake and body weight, future studies should investigate whether GLP-1 agonists influence hypothalamic neuropeptide expression or signaling cascades in MC4R-deficient models

Rarely, some patients may experience a mild headache or light bruising

Immune cells responsible for inflammation express the vitamin D receptor, and vitamin D successfully suppresses chronic inflammation in multiple settings, while vitamin D deficiency is associated with a pro-inflammatory state (Mohd 2022

Lancet Oncol (2020) 21:64554