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Adjustments to dosing or compound selection happen based on lab data and reported patient experience, not according to a fixed protocol applied the same way to every patient

Mechanisms of apoptosis inhibition by a novel ring-substituted diindolylmethane (1,1-bis[3'-(5-methoxy indolyl)]-1-[p-t-butylphenyl]methane) (BMIPTM) in leukemic cells

Hintz RL, Liu F

Its main mechanism appears to be its interaction with the nitric oxide (NO) system and its ability to upregulate growth factors like Vascular Endothelial Growth Factor (VEGF)
