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2 nd ed: Thomson Reuters
Elevated extracellular cystine levels can enhance glutaminase activity by depleting intracellular glutamate, thereby increasing cancer cell reliance on glutaminase for glutamate replenishment
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For example, the two endogenous ligands of CCR7, CCL19 and CCL21, have been shown to be biased, differentially activating G proteins and -arrestins [93]
