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As IRE1 is the most evolutionarily conserved UPR sensor, we investigated whether it also determines ferroptosis sensitivity in lower organisms

HMGB1 and Toll-like receptors: potential therapeutic targets in autoimmune diseases

doi: 10.2337/diabetes.52.2.300

Graham Noctor, et al The glutathione system and its regulation by neurohormone melatonin in the central nervous system Cent Nerv Syst Agents Med Chem 2010 Dec 1
