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They must be handled only by trained individuals in appropriate laboratory settings

Under normal conditions, about 14% of oxygen is not reduced completely and is transferred to ROS, primarily to superoxide radical anion by one-electron reduction of oxygen (Iacobini et al

In their review, Doets et al

Many therapeutic protocols use doses of 1,0002,000 micrograms daily or weeklyhundreds of times the physiological requirementwithout adverse effects
