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discovered that MWCNT instillation reduced the mRNA expression of CPT1, CPT2, and PPAR coactivator 1 alpha in permeabilized bronchoalveolar lavage cells, accompanied by elevated oxidative stress in alveolar macrophages and inflammatory injury of murine lung tissues ( According to the current evidence, CPT activation can exert either a beneficial or harmful effect during the development of pulmonary diseases

Bower JE, Lacchetti C, Alici Y, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Cavallini G., Paulis G

Whole-body loss of SREBP-1 prevents hepatic steatosis in Lep ob/ob mice indicating that SREBP-1 proteins are required for TAG accumulation in the liver (349)