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If youre considering B12 therapy, Trim Body M.D
For injections given under the skin, the most common protocol is to give 250 micrograms once a week for an initial six weeks

The most robust theory is that metformin disrupts the B12-intrinsic factor (IF) complex uptake at the ileal cell surface receptor (Cubilin receptor) which is known to be calcium dependent

Sharabi A, Cohen E, Sulkes J, Garty M
