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The release of damage associated molecular patterns (DAMPs) upon cell death, together with the release of reactive oxygen species (ROS) in oxidative bursts, further amplifies genotoxic cell stress (38)

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and protein interaction networks were mapped using the Search Tool for the Retrieval of Interacting Genes/Proteins database (version 11.5

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There is a single nucleotide gene polymorphism C677T in the MTHFR coding gene and mutations in this enzyme lead to decreased activity and heat resistance, resulting in increased tHcy levels

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