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eNOS uncoupling is particularly significant in the context of cardiovascular diseases, where it leads to superoxide anion production instead of NO [68]
PEGs that have a molecular weight of 4004000 Da can only cross the intestinal mucosa under conditions of barrier integrity loss
[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Haist M, Stege H, Grabbe S, Bros M
In terms of anti-inflammatory effects, propolis regulates key signaling pathways such as NF-B and MAPK to inhibit the release of pro-inflammatory factors like TNF- and IL-6, thereby alleviating acute and chronic inflammatory responses [57]
