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Tranexamic acid controls melanogenesisthe process by which the skin produces dark pigmentthereby helping to effectively brighten existing dark circles
By acting on the amylin receptor, cagrilintide helps modulate these functions
However, systemically reducing p16 Ink4 a or p53-p21 Cip1/Waf1 expression is likely to increase cancer risk since p53 , p21 Cip1/Waf1 , and p16 Ink4a global KO mice have a high prevalence of cancer and hence a shorter lifespan than control mice (250-253)
J Chronic Dis
