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J Clin Neurophysiol 36(6):443451

Further studies are necessary to clearly delineate the major NAD + biosynthetic pathways and NAD + consumption routes during macrophage phenotypic transition to determine whether the observed decline in NAD + levels depends on context and time and to determine the molecular mechanisms through which NAD + levels alter macrophage polarization states and functions

Yu et al., 2020), suggesting a positive feedback between PKM2 and drug resistance
