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Copper(II) ions serve as essential cofactors for numerous enzymes involved in tissue repair, including lysyl oxidase (collagen cross-linking), cytochrome c oxidase (mitochondrial energy production), and superoxide dismutase (antioxidant defense)

[PMID: 16007097 DOI: 10.1038/nm1267] [DOI] [PMC free article] [PubMed] [Google Scholar] 42.Ji X, Tan W, Zhang C, Zhai Y, Hsueh Y, Zhang Z, Zhang C, Lu Y, Duan B, Tan G, Na R, Deng G, Niu G

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In turn, HGF is believed to decrease liver enzyme levels in hemodialysis patients possibly through hepatocyte proliferation and accelerated liver repair