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Description
Mitochondrial complex I defects in aging
The approval is supported by data from the Phase III NRG-GY018/ KEYNOTE-868 trial, in which the regimen reduced the risk of disease progression or death by 40% in patients whose cancer was mismatch repair proficient and by 70% in patients whose cancer was mismatch repair deficient, when compared to placebo with carboplatin and paclitaxel followed by placebo alone
The supernatant was discarded and samples were resuspended in 5 Laemmli buffer

Angewan Chem Int Ed Eng 47: 51865189