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Description
To induce acute liver injury, 8-week-old NSI mice received two consecutive intraperitoneal injections of DMN (7 mg/kg, Sigma, 1.0% dissolved in saline)
Our experience suggests that while a systemic dose will eventually reach the ankle, a localized dose may create a much higher concentration gradient in the target tissue for a more potent and immediate effect

Pain typically concentrates at the inferior pole of the patella, where the tendon attaches to the kneecap

Poly-L-Lactic Acid was first used in cosmetic surgery as dissolving sutures
