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Stronger ligandprotein binding affinity and improved stability are indicated by lower G_bind values

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The response rate of the liquid-biopsy group ( n = 66) and the tissue-biopsy group ( n = 60) were 48% and 50%, respectively

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3.1 In vitro models: from conventional to 3D spheroid and organoid models Like in other human tumors, traditional cultures of cell monolayer remain widely used in research, providing a controlled environment for rapid drug screening and genetic manipulation

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