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Serum metabolites in the ScWAT showed a positive correlation between HDL and ScCPT2 ( r = 0.231, p = 0.015) and ScECHS1 ( r = 0.192, p = 0.044), whereas in the omWAT, there was a negative correlation between glucose and ScCPT2 ( r = 0.202, p = 0.05), TG and ScCPT2 ( r = 0.217, p = 0.04), and TG and ScACAA2 ( r = 0.215, p = 0.044) (Additional file 1: Tables 3 and 4)

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DISCUSSION Only recently has there been evidence that L-carnitine content in skeletal muscle can be increased when supplementation is coincided with a strong insulin response (25, 31)