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In TJA, where the consequences of wound failure and PJI are severe, the absence of validated safety data is clinically meaningful

Statements Author contributions TSo: Conceptualization, Methodology, Project administration, Writingoriginal draft, Writingreview and editing

In fact, a 2023 paper published in the Journal of Cerebral Blood Flow & Metabolism reported that methylene blue (in similar doses studied by researchers at The University of Texas at Austin who claimed the compound had memory-enhancing properties) led to a 8% decrease in human brain blood flow
