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10.1073/pnas.0907722106 Proc Natl Acad Sci U S A

NRF1 regulates gene expression related to mitochondrial respiration, heme formation, and the import and assembly of mitochondrial proteins

Refrain from jumping, running, heavy lifting, and any other strenuous exercise for a few weeks after surgery

However, wild-type p53 could delay induction of ferroptosis by regulating its transcriptional target CDKN1A (encoding p21)
