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Chemical Basis of Nanoparticle-Induced Ferroptosis in Cancer Management An equivalent but distinct strategy for treating tumors is ferroptosis therapy, which employs methods to produce ROS including OH, leading to the accumulation of lethal lipid peroxides, based on the significant polyunsaturated phospholipids peroxidation on the cellular membrane

DNA isolation and genotyping Total genomic DNA was extracted from 5 ml of EDTA-treated peripheral whole blood using the standard salting-out method 55