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Front Pharmacol:1590 Irving GR, Howells LM, Sale S, Kralj-Hans I, Atkin WS, Clark SK, Britton RG, Jones DJ, Scott EN, Berry DP, Hemingway D (2013) Prolonged biologically active colonic tissue levels of curcumin achieved after oral administrationa clinical pilot study including assessment of patient acceptability

Yes, research subjects with pre-existing metabolic conditions, such as pre-diabetes, type 2 diabetes, or metabolic syndrome, have a compromised ability to manage blood glucose
STI suggests a tolerance mechanism that allows plants to retain development even in the presence of abiotic factors such as hazardous metal levels 48
