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2014 Aug;14(4):33642

Scientists have studied it in models related to tendon-to-bone healing, ligament repair, nitric oxide signaling, angiogenesis, and neurological function
ALA possesses functional pleiotropism across various signal transduction pathways

In these studies, breast tumors expressing a dnIGF-1R that colonize the bone display reduced mitosis and increased apoptosis compared to tumors expressing functional IGF-1R [135]
