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This advancement could significantly impact the treatment strategies for Alzheimers and related tauopathies, offering new hope for millions of patients suffering from these debilitating conditions, said Sagar Gaikwad, first author of the study and postdoctoral fellow at UTMB
The attachment of ubiquitin to substrate proteins is carried out by an ATP-dependent mechanism that requires the sequential activity of three enzymes: ubiquitin-activating enzyme, ubiquitin-conjugating enzyme, and ubiquitin ligase (E3) (Shenoy et al., 2001
2013 Apr 18;6:767482
A representative gif: Bride of the Water God Vol
