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This approach is used to explore multi-pathway recovery involving angiogenesis, oxidative stress reduction, and cellular energy optimization across complex injury and aging models
It appears to rejuvenate aging cells by restoring youthful gene expression patterns
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The authors suggest an implication of the phosphorylated CREB, mediated by PI-3K and MAPK signaling pathways, that is known to decrease neurotoxicity and oxidative stress-induced neuronal death (Du and Montminy, 1998
